Scope and Contents

The collection documents Parke, Davis and Company, one of America's oldest and largest drug makers. Parke, Davis had the first research laboratory in the American pharmaceutical industry. The company played a major role in the development of some of the principle new drugs of the twentieth century and pioneered the field of drug standardization. They were one of the first American firms to produce antitoxins, hormones, and other biologicals. They introduced new and important drugs such as adrenalin, dilantin, chlorenpleniol, and other antibiotics. They also did important research on vitamins, disinfectants, and pencillin.

The collection contains complete documentaion of all the research activities done, including research laboratory notes, correspondence, and published papers. The collection also contains corporate, financial, advertising and sales materials, photographs, and audiovisual materials. The collection is important for those researchers interested in the history of public health, the history of biologicals, pharmaceutical manufacturing and business history.

Arrangement

Collection is divided into 13 series.

Series 1: Corporate Materials, 1887-1951

Series 2: Financial Materials, 1880-1970

Series 3: Employee/Personnel Materials, 1900-1989

Series 4: Advertising/Sales Materials, 1868-1980

Series 5: Photographs, 1866-1992

Series 6: Notebooks, 1908-1968

Series 7: Control Department Records, 1884-1931

Series 8: Formulas, 1882-1967

Series 9: Equipment Data Files, 1922-1978

Series 10: Publications, 1968-1988

Series 11: Research Materials, 1920-1978

Series 12: Drawings, 1911-1971

Series 13: Addenda, 1867-1970

Series 14: Audio Materials, 1956-1957

Historical

Parke, Davis and Company traces it's origins to Samuel Pearce Duffield (1833-1916), a physician and pharmacist. Duffield was born in Carlisle, Pennsylvania and his family moved to Detroit when he was an infant. Duffield graduated from the University of Michigan in 1854 and he attended medical school at the University of Pennsylvania, latter leaving for Germany where he studied chemistry and sought treatment for his eyesight. He subsequently earned a Doctor of Philosophy from Ludwig University at Giessen in Germany. Duffield returned to Detroit in 1858 and established a retail drugstore with a strong interest in manufacturing pharmaceuticals. Duffield sought financial partners for his retail and manufacturing venture with A.L. Patrick and Francis C. Conant. Both men retracted their investments and Duffield met Hervey Coke Parke (1927-1899), a native of Bloomfield Hills, Michigan.

Duffield and Parke formed a formal partnership in 1866. George S. Davis, a third partner and traveling salesman previously with Farrand, Sheley and Company, was added 1867. Augustus F. Jennings joined the company as a partner to head manufacturing. The company became known as Duffield, Parke, Davis, & Jennings Company. Duffield withdrew in 1869 and the name Parke, Davis & Company was adopted in 1871. The company incorporated in 1875 and began planning world-wide scientific expeditions to discover new vegetable drugs such as Guarana, Bearsfoot, Eucalyptus Globulus, and Coca. The company first showed a profit in 1876, and the first dividend paid to shareholders in 1878 and dividends paid until mid-1960s. Research was a major activity of the company.

In 1907, Parke, Davis and Company bought 340 acres in northeast Avon Township, Michigan, and called it Parkedale Farm. The farm was dedicated on October 8, 1908, and included sterilization rooms and a vaccine propagating building. By 1909 the farm included 200 horses, 25 to 50 cattle, 150 sheep, and employed 20 men. The horses produced the antitoxin for diphtheria and tetanus, the cattle produced a vaccine for smallpox preventatives, and the sheep made serum. Only the healthiest animals were used and all were well cared for. Exotic plants were also grown on the site and used for drugs. Parke-Davis' chief products were antitoxins and vaccines as well as farm crops for feeding the animals. The farm continued to produce vaccines for diphtheria, scarlet fever, tetanus, smallpox, anthrax, and in the 1950s, the Salk polio vaccine.

Due to a weakening financial position, the company became susceptible to take-over, and was purchased by Warner-Lambert in 1970. Warner Lambert, was then acquired by Pfizer in 2000. In 2007, Pfizer closed its research facilities in Ann Arbor, Michigan.

Rochester Hills Museum at Voon Hoosen Farm (last accessed on September 29, 2021 https://www.rochesterhills.org/Museum/LocalHistory/ParkeDavisFarm.pdf)

Parke, Davis and Company. Detroit, Michigan, 1966.

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Smithsonian Libraries Trade Literature Collection

Trade catalogs related to Parke, Davis & Co.; Warner-Lambert; Pfizer Pharmaceuticals; and Pfizer, Inc.

Parke, Davis & Company records, 1892-1959

Scrapbook of clippings, 1929-44; Excursions & Announcements, 1892-1902; and company newsletters.

Drug Industry Documents was created by the University of California San Francisco Library in collaboration with faculty members C. Seth Landefeld, MD and Michael Steinman, MD. Originally established to house documents from an off-label marketing lawsuit against Parke-Davis (), the archive has grown to include documents from additional sources illustrating how the pharmaceutical industry, academic journals and institutions, continuing medical education organizations and regulatory/funding agencies operate in ways that are detrimental to public health.