Summary
- Collection ID:
- NMAH.AC.0623
- Creators:
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Jerome and Dorothy Lemelson Center for the Study of Invention and Innovation.
- Dates:
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1997-06-05
- Languages:
-
- Physical Description:
-
- Repository:
-
Scope and Contents note
Scope and Contents note
Original videos documenting Curt I. Civins's discovery of the cell surface protein that makes stem cell selection possible; and interviews with Kenneth Kinsler and Bert Vogelstein.
Biographical/Historical note
Biographical/Historical note
In the 1970s when Civin began stem cell research, little was known about progeniters, the cells of all other blood lineages. Civin thought that stem cells had their own identifying surface proteins. To test this, he immunized mice with leukemia cells, some of which he supposed might have that peculiar protein and then harvested the resulting immunoglobulins and reproduced them as monoclonal antibodies. In 1981, Civin discovered an antibody that bound to 1% of marrow cells.
Administration
Ownership and Custodial History
This videodocumentation was created by the Jerome and Dorothy Lemelson Center for the Study of Invention and Innovation and NMAH staff Terry Sharrer of the Division of Science, Medicine and Society. Tranferred to the Archives Center October, 1997.
Immediate Source of Acquisiton
Created by the Jerome and Dorothy Lemelson Center for the Study of Invention and Innovation, National Museum of American History, 1997.
Processing Information
Collection processed by Alison Oswald, 1998.
Using the Collection
Terms Governing Use and Reproduction
Collection items available for reproduction, but the Archives Center makes no guarantees concerning copyright restrictions. Other intellectual property rights may apply. Archives Center cost-recovery and use fees may apply when requesting reproductions. Signed releases in file.
Conditions Governing Access
Collection is open for research but the original videos are stored off-site and special arrangements must be made to work with it. Contact the Archives Center for information at archivescenter@si.edu or 202-633-3270.
Preferred Citation
Curt I. Civin Video Documentation, June 5, 1997, Archives Center, National Museum of American History.
Related Archival Materials
Prototype of stem cell selector instrument housed in Division of Science and Medicine and Society (now Division of Medicine and Science).
Keywords
Archives Center, National Museum of American History
P.O. Box 37012
Suite 1100, MRC 601
Washington, D.C. 20013-7012
archivescenter@si.edu
