Curt I. Civin Video Documentation

Summary
Collection ID:
NMAH.AC.0623
Creators:
Vogelstein, Bert
Kinsler, Kenneth
Sharrer, Terry
Civin, Curt I.
Jerome and Dorothy Lemelson Center for the Study of Invention and Innovation.
Dates:
1997 June 5
Languages:
English
Physical Description:
0.25 Cubic feet
Repository:

Scope and Contents note
Scope and Contents note
Original videos documenting Curt I. Civins's discovery of the cell surface protein that makes stem cell selection possible; and interviews with Kenneth Kinsler and Bert Vogelstein.

Arrangement
Arrangement
1 series.

Biographical/Historical note
Biographical/Historical note
In the 1970s when Civin began stem cell research, little was known about progeniters, the cells of all other blood lineages. Civin thought that stem cells had their own identifying surface proteins. To test this, he immunized mice with leukemia cells, some of which he supposed might have that peculiar protein and then harvested the resulting immunoglobulins and reproduced them as monoclonal antibodies. In 1981, Civin discovered an antibody that bound to 1% of marrow cells.

Administration
Processing Information
Collection processed by Alison Oswald, 1998.
Author
Alison L. Oswald
Immediate Source of Acquisiton
National Museum of American History, Smithsonian Institution, Dept. of History.,Lemelson Center for the Study of Invention and Innovation, Room 1016, MRC 604, 12th & Constitution Ave., N.W., Washington, D.C. 20560.,Made for NMAH.,1997.3168.

Using the Collection
Preferred Citation
Curt I. Civin Video Documentation, June 5, 1997, Archives Center, National Museum of American History.
Terms Governing Use and Reproduction
Collection items available for reproduction, but the Archives Center makes no guarantees concerning copyright restrictions. Other intellectual property rights may apply. Archives Center cost-recovery and use fees may apply when requesting reproductions. Signed releases in file.
Conditions Governing Access
Collection is open for research.

Related Archival Materials
Prototype of stem cell selector instrument housed in Division of Science and Medicine and Society.

Ownership and Custodial History
Ownership and Custodial History
This videodocumentation was created by the Jerome and Dorothy Lemelson Center for the Study of Invention and Innovation and NMAH staff Terry Sharrer of the Division of Science, Medicine and Society. Tranferred to the Archives Center October, 1997.

Keywords
Keywords table of terms and types.
Keyword Terms Keyword Types
Tumors in children -- 1970-2000 Topic Search Smithsonian Collections Search ArchiveGrid
Videotapes -- 1990-2000 Type Search Smithsonian Collections Search ArchiveGrid
Physicians -- 1950-2000 Topic Search Smithsonian Collections Search ArchiveGrid
Stem cells Topic Search Smithsonian Collections Search ArchiveGrid
Oncology -- 1970-2000 Topic Search Smithsonian Collections Search ArchiveGrid
Oral history -- 1990-2000 Type Search Smithsonian Collections Search ArchiveGrid
Leukemia in children -- 1970-2000 Topic Search Smithsonian Collections Search ArchiveGrid
Medicine -- 1970-2000 Topic Search Smithsonian Collections Search ArchiveGrid
Cancer research -- 1970-2000 Topic Search Smithsonian Collections Search ArchiveGrid
Interviews -- 1980-2000 Type Search Smithsonian Collections Search ArchiveGrid
Cell growth -- 1970-2000 Topic Search Smithsonian Collections Search ArchiveGrid
Becton Dickinson. Corporate Name Search Smithsonian Collections Search ArchiveGrid
Johns Hopkins University Corporate Name Search Smithsonian Collections Search ArchiveGrid
Baxter Healthcare Corporation. Corporate Name Search Smithsonian Collections Search ArchiveGrid

Repository Contact
Archives Center, National Museum of American History
P.O. Box 37012
Suite 1100, MRC 601
Washington, D.C. 20013-7012
archivescenter@si.edu
http://americanhistory.si.edu/archives