The Center for the Study of Man (CSM) was a bureau level division of the Smithsonian Institution. These records were maintained by the Program Coordinator, Samuel L. Stanley, and include correspondence, scholarly papers, transcripts, administrative materials, photgraphs, and audio recordings. The materials relate to conferences and programs in which CSM took part.

The papers of Aleš Hrdlička, curator in the Division of Physical Anthropology, Department of Anthropology, United States National Museum of the Smithsonian Institution, offer considerable insight into the development of physical anthropology in the first half of this century. The papers include honors bestowed on Hrdlička, autobiographical notes, correspondence with many of the leading anthropologists of the day, anthropometric and osteometric measurements and observations (forming most of the collection), extensive photographs of Hrdlička's field work, manuscripts, research materials, and "My Journeys" (essentially a diary Hrdlička kept of his field work). In addition, there is material of a personal nature. The papers date from 1875 to 1966, but the bulk of the materials date from 1903 to 1943, the time of Hrdlička's career at the USNM.

Printed advertisements, scrapbooks, correspondence, marketing research, radio commercial scripts, photographs, proof sheets, reports, newspaper clippings, magazine articles, television commercial storyboards, blueprints, legal documents, and audiovisual materials primarily documenting the history, business practices, and advertising campaigns of the Hills Bros. Coffee Company, Incorporated. Collection documents the professional and private lives of the Hills family; insight into the cultivation, production, and selling of coffee; and construction of the San Francisco-Oakland Bay Bridge.

The papers document the life and work of William R. Hutton, a civil engineer during the late 1800s to the early 1900s. Materials include diaries, notebooks, correspondence, letterpress copy book, printed materials, publications, specifications, photographs, drawings, and maps that document the construction of several architectural and engineering projects during this period. Most notable are the records containing information related to the construction of the Chesapeake and Ohio Canal, Hudson River Tunnel, the Washington Aqueduct, the Kanawha River Canal, and the Washington/Harlem River Bridge. There are also several records about railroads in the state of Maryland, the District of Columbia and elsewhere, including the Western Maryland Railroad, Baltimore and Ohio Railroad, Colorado Midlands Railway, Baltimore and Drum Point Railroad, the Northern Adirondack Railroad, and the Pittsfield and Williamstown Railroad. The records can be used to track the progression of these projects, and engineering innovation during the late 1800s to the early 1900s.

Collection documents activist and educator Elaine Ostroff who advocated for improved access for people with disabilities in public places, co-founded the Adaptive Environments Center and who taught universal design in several institutions.

The records document the development and use of Reddy Kilowatt, a cartoon figure trademark created in 1926 by Ashton B. Collins, Sr. More than 150 investor-owned electric utilities in the United States and at least twelve foreign countries licensed the use of the Reddy Kilowatt trademark. The records include a wide range of textual and visual materials and sound and moving image recordings.

The Priscilla Reining papers, 1916-2007, primarily document the professional life of Reining, a social anthropologist and Africanist who worked for the American Association for the Advancement of Science (AAAS) from 1974 to 1989. Her area of specialty was sub-Saharan Africa, specializing in desertification, land tenure, land use, kinship, population, fertility, and HIV/AIDS. During the 1970s, she pioneered the use of satellite imagery in conjunction with ethnographic data. She is also known for her ground-breaking research in the late 1980s that showed that uncircumcised men were more susceptible to contracting HIV/AIDS than circumcised men. The collection contains correspondence, field research, research files, writings, day planners, teaching files, student files, photographs, maps, sound recordings, and electronic records. Reining's research files, particularly on the Red Lake Ojibwa, the Haya, HIV/AIDS, and satellite imagery, form a significant portion of the collection.

The papers document the life and activism of Grayce Uyehara who was a pivotal figure within the Redress Movement and sought reparations for the incarceration of Japanese Americans during World War II.