Janese Swanson developed video game software, a website, and an array of toys and gadgets aimed at making technology more accessible to girls. The collection contains approximately six hours of original and reference video footage of Swanson's Innovative Lives Presentation, in which she discussed her background and demonstrated her inventions with her daughter, Jackie. The material also includes a brief interview.

The collection consists of 109 cubic feet of material, primarily photographs with some additional documentation, covering aerospace topics. The bulk of the material relates to US space exploration, including extensive photo files on US manned missions through the Space Shuttle, and satellite and sounding rocket work. The first series consists of unmanned spacecraft material, the second series consists of manned spacecraft material, and the third series consists of aircraft material.

President of Tuskegee Normal and Industrial Institute (later Tukegee Institute; now Tuskegee University) from 1935 - 1953 and founder of the United Negro College Fund (1944). Patterson was born on October 10, 1901. Orphaned at age two, he was raised by his eldest sister, Wilhelmina (Bess), a school teacher in Texas. He studied at Iowa State College, where he received a doctorate in veterinary medicine in 1923 and a master of science degree in 1927. Five years later, he was awarded a second doctorate degree from Cornell University. Patterson taught veterinary science for four years at Virginia State College, where he was also Director of Agriculture. His tenure at Tuskegee University started in 1928 and spanned almost 25 years, first as head of the veterinary division, then as the director of the School of Agriculture and finally as Tuskegee's third president. He married Catherine Elizabeth Moton, daughter of Tuskegee University's second president, Dr. Robert R. Moton. Patterson also founded the School of Veterinary Medicine at Tuskegee in 1944, the same year he founded the United Negro College Fund (UNCF). The UNCF continues today as a critical source of annual income for a consortium of Historically Black Colleges and Universities, Tuskegee University among them.

The collection contains the project design records of Rudy J. Favretti. , a landscape architect and professor noted for his extensive work in historical restoration of gardens, parks, and landscapes. He donated his collection of garden design files, plans, and images to the Smithsonian's Archives of American Gardens in March 2011.

This collection contains 5 photographs of that were collected by William W. Wotherspoon that depict Goyathlay (Geronimo) and Chatto. The bulk of the photos were shot while Goyathlay and Chatto were a prisoners of war at the Mount Vernon Barracks in Alabama from 1888-1894.

The Dr. Matilda Arabella Evans Collection of documents how she broke boundaries as one of the first African American women physicians to have her own practice. The collection highlights her role as a physician and the great impact she had on the health and welfare of the African American community. The collection is comprised of educational material, business records, photographs, publications, and reference materials collected by and about Evans and her work.

Approx. 1,065 color photographs (chromogenic prints), negatives and slides of rural scenes, mostly in Kansas.

The collection is the result of research conducted by Dr. Alixa Naff relating to the study of the early Arab immigrant experience in the United States from about 1880-World War II. The study began with oral history interviews in 1962 and became a major project in 1980 with a grant from the National Endowment for the Humanities. It documents the assimilation of Arabic speaking immigrants in the United States.

The George Henry Mills Collection was donated to the National Air and Space Museum in 1994 by Mills' daughter, Mrs. Georgia Mills Head.

Photographic prints and copy negatives made by Major Otto Holstein in and around the ruins of Chan Chan, Peru between 1925 and 1926. Some of these photographs were later used by Holstein to illustrate his article publication "Chan-Chan: Capital of the Great Chimu" in the American Geographical Society's publication Geographical Review.